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Symbol
Name
ID
Igh-J
immunoglobulin heavy chain, joining region
MGI:96461
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
abnormal B cell differentiation
abnormal B cell receptor editing
decreased immature B cell number
decreased transitional stage B cell number
decreased transitional stage T1 B cell number
decreased transitional stage T2 B cell number
increased immature B cell number
increased late pro-B cell number
increased pro-B cell number
arrested B cell differentiation
decreased mature B cell number
absent mature B cells
decreased B-1a cell number
increased mature B cell number
increased marginal zone B cell number
decreased B cell number
absent B cells
decreased pre-B cell number
increased pre-B cell number
abnormal T cell number
decreased T cell number
abnormal marginal zone B cell morphology
decreased spleen weight
spleen hypoplasia
abnormal immunoglobulin level
decreased IgG1 level
decreased IgG2b level
decreased IgG3 level
decreased IgG level
increased IgG level
decreased IgM level
increased IgM level
abnormal immune serum protein physiology
increased susceptibility to induced arthritis
increased anti-double stranded DNA antibody level
Availability Mouse Genotype
Igh-Jtm1(3H9-VDJ)Mwg/Igh-Jtm1(3H9-VDJ)Mwg
Igh-Jtm1(CB20)Riho/Igh-Jtm1(CB20)Riho
Igh-Jtm1.1Lave/Igh-Jtm1.1Lave
Igh-Jtm1Cgn/Igh-Jtm1Cgn
Igh-Jtm1Jkbv/Igh-Jtm1Jkbv
Igh-Jtm2.1(4E10)Lave/Igh-Jtm2.1(4E10)Lave
Igh-Jtm3(3H9-VDJ*)Mwg/Igh-Jtm3(3H9-VDJ*)Mwg
Igh-Jtm3.1(48d)Lave/Igh-Jtm3.1(48d)Lave *
Igh-Jtm1(CB20)Riho/Igh-J+
Igh-Jtm1(VDJ-KL25)Zbz/Igh-J+
Igh-Jtm1(VDJ-VI10)Zbz/Igh-J+
Igh-Jtm1.1Lave/Igh-J+
Igh-Jtm1Cgn/Igh-J+
Igh-Jtm2(3H9-VDJ*)Mwg/Igh-J+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory